Amoxil is an effective and relatively safe remedy for the treatment of infectious diseases. But if patients are intolerant of its components, the use of analogues that have similar therapeutic properties is required.
How to choose an analog?
Amoxil is a popular representative of the clinical and pharmacological group of semi—synthetic penicillins among doctors and their patients. In the form of tablets and suspensions, it is usually used at home for the treatment of infectious and inflammatory pathologies, and in the hospital therapy is carried out with an injection solution. Amoxil substitutes can be divided into two groups:
- structural analogues contain the same active substance, exhibit similar therapeutic effects in nature and severity;
- active analogues have approximately the same therapeutic effect, but it is due to another active substance.
The powerful antibacterial and antimicrobial properties of Amoxil are determined by amoxicillin, which quickly copes with many gram-negative and gram-positive microorganisms. The second most important component is clavulanic acid, which prevents pathogenic bacteria from developing resistance (resistance) to the drug.
Penclav Tablets
The active substances are amoxicillin and clavulanic acid — the same components that are part of the Amoxil. Penclav is included in the therapeutic regimens of patients with such diseases:
- infections of ENT organs, lower and upper respiratory tract;
- infections of the skin and soft tissues, bones and joints;
- odontogenic infections, including those caused by dental root pathologies;
- infections of internal organs, including the urogenital tract.
This is one of the best antibiotics for complicated pharyngitis and sore throats, acute cystitis and already chronic dental diseases.
Unlike Amoxil, which is available in three dosage forms, Penclav can only be purchased in the form of tablets with an adult dosage.
Penclav is usually taken 1 tablet three times during the day at equal time intervals. The duration of therapy varies from five days to two weeks, depending on the severity of the diagnosed disease. If necessary, it is resumed after a 10-day break.
The antibiotic Amoxicillin
Amoxicillin has a wide spectrum of action and pronounced bactericidal properties. It is active against aerobic gram-positive bacteria, staphylococci, streptococci, aerobic gram-negative bacteria that provoke the development of gonorrhea and meningitis, E. coli, shigella, klebsiella. The difference between Amoxil and Amoxicillin in the composition of drugs. And they determine the pharmacodynamic and pharmacokinetic parameters:
- the active substance of Amoxicillin is directly amoxicillin, in Amoxil there is also clavulanic acid;
- infectious agents develop resistance (resistance) to Amoxicillin faster.
Tablets are taken orally, washed down with water, before or after meals. Dosages and the period of treatment by the doctor are prescribed individually, taking into account clinical indications. But it is not recommended to use the drug for longer than 10 days.
Unlike Amoxil, side effects in adults after taking Amoxicillin occur more often. But only if you take the latter in the form of tablets. Recently, many domestic pharmaceutical factories have been producing it in capsules, the gelatin shell of which contributes to the dosed release of the active substance. And this significantly minimizes the likelihood of side effects.
About the safety of Amoxiclav and analogues
In Amoxil analogues, not only indications are common, but also restrictions on treatment. So, drugs in the form of tablets are not intended for the therapy of children under 12 years of age. Pregnancy and breastfeeding are not included in the list of contraindications. But both Amoxiclav and its analogues are prescribed to women in any trimester and during lactation after assessing the benefits for them and the risks to the fetus or child.
In combination with alcohol, Amoxiclav will lose most of its pharmacological effects. Ethyl alcohol will slow down the active substances, so that they will be excreted unchanged from the body. The probability of the manifestation of pronounced side effects by an antibacterial agent also increases significantly.